About PKRxiv
PKRxiv was developed in 2024 by a team led by Dr Adeniyi Olagunju at the University of Liverpool, United Kingdom.
Key features
Fully Anonymized Datasets
Fully anonymised datasets from studies whose primary outcomes are already published or accepted for publication in a peer-reviewed journal.
Interactive Visualization Dashboard
Interactive visualisation dashboard for exploration of available datasets in aggregated format per therapeutic is accessible by all users;
Collaborative Data Sharing
Data sharing on PKRxiv is collaborative, with functionalities to enable both contributor-led and in-house data curation.
Managed Open Access
Open access is managed, with requirement for user account creation before access to data request and data contribution sections.
Individual-Level Data Access
Access to individual-level harmonised and pooled PK and covariates data per therapeutic.
Compliance with Data Sharing Policies
Differentiated data sharing model to facilitate compliance with different organisational data sharing policies.
Support for Data Curation
Functionalities to support both contributor-initiated and in-house data curation using the PKRxiv template.
DOI Assignment
Every dataset curated on PKRxiv is assigned a digital object identifier (DOI) by the University of Liverpool to facilitate findability, attribution and preservation.
Industry Standard Development
The platform has been developed to the highest industry standards with the University of Liverpool as the legal sponsor.
PKRxiv overarching goals
- To serve as the gold-standard resource for pharmacometricians looking for robust data to quality pharmacokinetic models for a broad range of therapeutics across different populations.
- To provide reliable, globally representative benchmark for pharmacokinetic parameters for therapeutics in key populations through harmonisation, pooling and meta-analysis of published data.
- To provide the global clinical pharmacologists community with a bespoke platform to satisfy funders’, institutional and publishers’ requirements for open data sharing.
Funding
PKRxiv is part of a comprehensive research programme funded by the Wellcome Trust, an independent charity funding research to improve human and animal health located in the UK.
